Fagron Concepts

Nourisil™ MD contains a unique blend of silicones and Vitamin E to improve the appearance of scars and maintain the skin’s moisture balance.
SyrSpend® SF PH4 is Fagron's innovative oral suspension vehicle, compatible with a wide range of API's and superior to traditional suspension vehicles
An innovative solution for dermatological care.

SyrSpend® SF PH4 Liquid and Alka Dry

SyrSpend® SF PH4 Liquid and Alka Dry

SyrSpend® SF is Fagron’s innovative family of sugar-free oral suspending vehicles. These vehicles provide an excellent formulation for easy preparation of smooth, elegant oral suspensions to achieve maximum patient satisfaction and compliance.

Fagron UK currently supply SyrSpend® SF PH4 (liquid) in cherry flavour and unflavoured and SyrSpend® SF Alka Dry in cherry and unflavoured bulk powder.

What are the benefits of using SyrSpend® SF PH4?

  • Free of sugars, alcohol, parabens, sorbitol, gluten and colourants.
  • Active Suspending Technology helps prevent the API settling, enhancing homogenisation for improved dosage accuracy.
  • Low osmolality (<50 mOsmol/kg) makes it GI-friendly and helps to improve patient satisfaction and compliance.
  • Compatible with a wide range of APIs - stability information for a wide range of APIs suspended in SyrSpend® SF is available, with further studies in progress. You can find compounding formulations for over 90 active ingredients with SyrSpend® SF PH4 on our free Compounding Matters formulation database. Click here to see our latest compatibility table.
  • Manufactured in a GMP certified facility to ensure high quality.
  • Suitable for use in the care of vulnerable patient groups, including Paediatrics, Hospitalised patients (N)ICU, nasogastric tube-fed patients, the elderly and more.
  • SyrSpend® SF PH4 is suitable for patients with special dietary requirements (Gluten and lactose intolerant and those on a ketogenic diet).

The video on the left of this page demonstrates how the SyrSpend® SF range is superior to a traditional oral suspension. The Active Suspending Technology in SyrSpend® SF allows for particles to be evenly dispersed and therefore leads to better dosage accuracy.

Have you read the Content Uniformity Article available for SyrSpend® SF?

The article shows:

  • Dosing of suspensions with SyrSpend® SF is extremely precise. None of the 74 APIs tested at room temperature and refrigerated temperature are out of specification. This immediately translates into patient safety. With SyrSpend® SF we know that we always deliver the right dose to the patient. This has never been shown on this scale for any other suspending agent.
  • Dosing with capsules on the other hand is very unreliable, especially when they are low dosed. More than 60% did not meet the criteria.
  • It would be beneficial to switch from capsules to SyrSpend® SF.

Please click the link below for the article. You can also find the link for the SyrSpend® SF Compatability Table at the bottom of this page.

 

For API's that experience degredation at a lower PH and require a more alkaline environment, we supply SyrSpend® SF Alka Dry. This product is sold as a bulk powder and is buffered to a higher PH, making it suitable for raw materials such as proton pump inhibitors (PPI) that require a higher PH for stability.

 

For more information about SyrSpend® SF or for a quotation please contact us on +44 (0)845 652 2525 or via info@fagron.co.uk.

View other Fagron Concepts

Nourisil™ MD contains a unique blend of silicones and Vitamin E to improve the appearance of scars and maintain the skin’s moisture balance.
Fagron UK supples gelatin and vegetarian Capsugel capsules of various sizes in packs of 500 or 1000.
An innovative solution for dermatological care.