Fagron Concepts

Fagron UK supply a variety of flavourings in 100ml packs and bulk sizes.
Fagron UK supples gelatin and vegetarian Capsugel capsules of various sizes in packs of 500 or 1000.
SyrSpend® SF PH4 is Fagron's innovative oral suspension vehicle, compatible with a wide range of API's and superior to traditional suspension vehicles

SyrSpend® SF PH4 Liquid and Alka Dry

SyrSpend® SF PH4 Liquid and Alka Dry

SyrSpend® SF is Fagron’s innovative family of sugar-free oral suspending vehicles. These vehicles provide an excellent formulation for easy preparation of smooth, elegant oral suspensions to achieve maximum patient satisfaction and compliance.

Fagron UK currently supply SyrSpend® SF PH4 (liquid) in cherry flavour and unflavoured and SyrSpend® SF Alka Dry in cherry and unflavoured bulk powder.

What are the benefits of using SyrSpend® SF PH4?

  • Free of sugars, alcohol, parabens, sorbitol, gluten and colourants.
  • Active Suspending Technology helps prevent the API settling, enhancing homogenisation for improved dosage accuracy.
  • Low osmolality (<50 mOsmol/kg) makes it GI-friendly and helps to improve patient satisfaction and compliance.
  • Compatible with a wide range of APIs - stability information for a wide range of APIs suspended in SyrSpend® SF is available, with further studies in progress. You can find compounding formulations for over 90 active ingredients with SyrSpend® SF PH4 on our free Compounding Matters formulation database. Click here to see our latest compatibility table.
  • Manufactured in a GMP certified facility to ensure high quality.
  • Suitable for use in the care of vulnerable patient groups, including Paediatrics, Hospitalised patients (N)ICU, nasogastric tube-fed patients, the elderly and more.
  • SyrSpend® SF PH4 is suitable for patients with special dietary requirements (Gluten and lactose intolerant and those on a ketogenic diet).

The video on the left of this page demonstrates how the SyrSpend® SF range is superior to a traditional oral suspension. The Active Suspending Technology in SyrSpend® SF allows for particles to be evenly dispersed and therefore leads to better dosage accuracy.

Have you read the Content Uniformity Article available for SyrSpend® SF?

The article shows:

  • Dosing of suspensions with SyrSpend® SF is extremely precise. None of the 74 APIs tested at room temperature and refrigerated temperature are out of specification. This immediately translates into patient safety. With SyrSpend® SF we know that we always deliver the right dose to the patient. This has never been shown on this scale for any other suspending agent.
  • Dosing with capsules on the other hand is very unreliable, especially when they are low dosed. More than 60% did not meet the criteria.
  • It would be beneficial to switch from capsules to SyrSpend® SF.

Please click the link below for the article. You can also find the link for the SyrSpend® SF Compatability Table at the bottom of this page.

 

For API's that experience degredation at a lower PH and require a more alkaline environment, we supply SyrSpend® SF Alka Dry. This product is sold as a bulk powder and is buffered to a higher PH, making it suitable for raw materials such as proton pump inhibitors (PPI) that require a higher PH for stability.

 

For more information about SyrSpend® SF or for a quotation please contact us on +44 (0)845 652 2525 or via info@fagron.co.uk.

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Fagron UK supply a variety of flavourings in 100ml packs and bulk sizes.
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Fagron UK supples gelatin and vegetarian Capsugel capsules of various sizes in packs of 500 or 1000.